[Reactivity differences between serums of patients infected with HIV-2 and HIV-1 antigens according to the patients' geographic origin].
Identifieur interne : 001613 ( Main/Exploration ); précédent : 001612; suivant : 001614[Reactivity differences between serums of patients infected with HIV-2 and HIV-1 antigens according to the patients' geographic origin].
Auteurs : F. Simon [France] ; I. Loussert-Ajaka ; G. Collin ; E. Gamba ; A. Powell-Smith ; S. Gadelle ; F. Brun-VézinetSource :
- Sante (Montrouge, France) [ 1157-5999 ]
Descripteurs français
- KwdFr :
- Afrique (ethnologie), Antigènes du VIH (immunologie), Dosage par radioimmunoprécipitation, France (épidémiologie), Humains, Infections à VIH (immunologie), Infections à VIH (sang), Infections à VIH (épidémiologie), Mali (épidémiologie), Réactions croisées, Surveillance de la population, Technique de Western, Techniques immunoenzymatiques, VIH-1 (Virus de l'Immunodéficience Humaine de type 1) (immunologie), VIH-2 (Virus de l'Immunodéficience Humaine de type 2) (immunologie), Études séroépidémiologiques.
- MESH :
- ethnologie : Afrique.
- immunologie : Antigènes du VIH, Infections à VIH, VIH-1 (Virus de l'Immunodéficience Humaine de type 1), VIH-2 (Virus de l'Immunodéficience Humaine de type 2).
- sang : Infections à VIH.
- épidémiologie : France, Infections à VIH, Mali.
- Dosage par radioimmunoprécipitation, Humains, Réactions croisées, Surveillance de la population, Technique de Western, Techniques immunoenzymatiques, Études séroépidémiologiques.
- Wicri :
English descriptors
- KwdEn :
- Africa (ethnology), Blotting, Western, Cross Reactions, France (epidemiology), HIV Antigens (immunology), HIV Infections (blood), HIV Infections (epidemiology), HIV Infections (immunology), HIV-1 (immunology), HIV-2 (immunology), Humans, Immunoenzyme Techniques, Mali (epidemiology), Population Surveillance, Radioimmunoprecipitation Assay, Seroepidemiologic Studies.
- MESH :
- chemical , immunology : HIV Antigens.
- geographic , epidemiology : France, Mali.
- geographic , ethnology : Africa.
- blood : HIV Infections.
- epidemiology : HIV Infections.
- immunology : HIV Infections, HIV-1, HIV-2.
- Blotting, Western, Cross Reactions, Humans, Immunoenzyme Techniques, Population Surveillance, Radioimmunoprecipitation Assay, Seroepidemiologic Studies.
Abstract
We tested 98 sera from HIV-2-infected patients for cross-reactivity with HIV-1 antigens in a competitive EIA test and western blotting. The sera were obtained during epidemiological surveys in Cape Verde Islands (n = 47) and Mali (n = 51). There were significantly more cross reactions with sera from Mali. Similar results were obtained with sera from African patients resident in France. Samples from HIV-2-infected patients from Burkina Faso, Ghana, Ivory Coast and Mali were more often reactive with HIV-1 antigens than were those from HIV-2-infected patients from the western Atlantic coast (Cape Verde, Guinea Bissau and Senegal). These data underline the importance of using specific tests for HIV-2 sero-positivity, and the need to include a panel of HIV-2-positive sera of different geographic origins in quality control kits.
PubMed: 8162361
Affiliations:
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Le document en format XML
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The sera were obtained during epidemiological surveys in Cape Verde Islands (n = 47) and Mali (n = 51). There were significantly more cross reactions with sera from Mali. Similar results were obtained with sera from African patients resident in France. Samples from HIV-2-infected patients from Burkina Faso, Ghana, Ivory Coast and Mali were more often reactive with HIV-1 antigens than were those from HIV-2-infected patients from the western Atlantic coast (Cape Verde, Guinea Bissau and Senegal). These data underline the importance of using specific tests for HIV-2 sero-positivity, and the need to include a panel of HIV-2-positive sera of different geographic origins in quality control kits.</div></front></TEI><affiliations><list><country><li>France</li></country><region><li>Île-de-France</li></region><settlement><li>Paris</li></settlement></list><tree><noCountry><name sortKey="Brun Vezinet, F" sort="Brun Vezinet, F" uniqKey="Brun Vezinet F" first="F" last="Brun-Vézinet">F. Brun-Vézinet</name><name sortKey="Collin, G" sort="Collin, G" uniqKey="Collin G" first="G" last="Collin">G. Collin</name><name sortKey="Gadelle, S" sort="Gadelle, S" uniqKey="Gadelle S" first="S" last="Gadelle">S. Gadelle</name><name sortKey="Gamba, E" sort="Gamba, E" uniqKey="Gamba E" first="E" last="Gamba">E. Gamba</name><name sortKey="Loussert Ajaka, I" sort="Loussert Ajaka, I" uniqKey="Loussert Ajaka I" first="I" last="Loussert-Ajaka">I. Loussert-Ajaka</name><name sortKey="Powell Smith, A" sort="Powell Smith, A" uniqKey="Powell Smith A" first="A" last="Powell-Smith">A. Powell-Smith</name></noCountry><country name="France"><region name="Île-de-France"><name sortKey="Simon, F" sort="Simon, F" uniqKey="Simon F" first="F" last="Simon">F. Simon</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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